In a 2021 chat with IGN, Dave Bautista hinted that Guardians of the Galaxy Vol.3 might mark the end of Drax the Destroyer's journey. He later joked on Twitter about aging out of the role.
Zoe Saldana revealed to The Hollywood Reporter in April 2023 that she's done portraying Gamora, sharing her emotional journey filming her final scenes.
After 11 appearances as Captain America, Chris Evans clarified on The View that he's moved on from the role, emphasizing its significance to him.
Jamie Lee Curtis bid farewell to Laurie Strode in a heartfelt Instagram post after wrapping up the latest Halloween movie, marking the end of her trilogy run.
Dylan O'Brien chose not to reprise his role as Stiles Stilinski in the Teen Wolf follow-up film, expressing fondness for the show but deciding to leave it in the past.
Henry Cavill announced he wouldn't return as Superman after confusion surrounding the character's future, acknowledging the inevitable changes in the industry.
Despite the success of Bridesmaids, Kristen Wiig ruled out a sequel, expressing excitement for new projects alongside co-writer Annie Mumolo.
Daniel Radcliffe clarified he's not involved in a Harry Potter TV series, signaling his willingness to let a new generation take on the iconic role.